Daily Archives: 5 July, 2012

Mediterranean diet aids pregnancy

Women wanting to get pregnant should eat a Mediterranean-style diet rich in avocados and olive oil but light in dairy and meat, an IVF conference has heard.

New research indicates a diet containing lots of monounsaturated fat – found in the fleshy green fruit, olive oil, as well as peanuts, almonds and cashews – can as much as triple the chance of success in women resorting to fertility treatment to conceive.

Specialists believe such a diet could help the majority of women wanting to get pregnant naturally as well.

By contrast eating lots of saturated fat, found in dairy products and red meat, appears to damage women’s fertility. High saturated fat intake has already been linked to lower sperm counts.

Dr Jorge Chavarro and colleagues at the Harvard School of Public Health in the US, looked at how intake of different types of fats affected success of IVF treatment in 147 women, mostly in their 30s.

They found the women who ate the most monounsaturated fat had up to three times the chance of giving birth via IVF as those who ate the least.

Specifically the top third, who derived on average 25 per cent of their calories from monounsaturated fat, has three times the chance of success compared to the bottom third, who derived on average nine per cent of their calories from it.

However, those who ate the most saturated fat produced two fewer eggs suitable for test-tube fertilisation than those who ate the least – nine compared to 11.

Dr Chavarro said: “As far as the best fat profile is concerned, this is the fat profile that you would find in a Mediterranean diet.”

However, he cautioned that the study was very small and the findings needed to be replicated in larger numbers before firm advice could be issued.

Mediterranean diet

Mediterranean diet

Nonetheless, he continued: “Even though we don’t know for sure if it will be of benefit, we do know it won’t be harmful.”

This was because numerous studies had shown Mediterranean-style diets to have a protective effect on health, particularly regarding heart disease.

The Harvard study also looked at the role of polyunsaturated fats, commonly thought to be healthy.


They found that – perhaps unexpectedly – women with higher intakes of polyunsaturated fats tended to have lower quality eggs.

But Dr Jorge, a nutritionist and epidemiologist, explained there were different types of polyunsaturated fats – some that could hinder fertility and others that could help.

He said the women in the study tended to eat lots of omega-six polyunsaturates, found in corn and canola oils.

He believed omega-three polyunsaturates, found in oily fish like salmon, were not harmful to fertility.

Women hoping to conceive should not stop eating them, he said.

The study, presented this week at the annual meeting of the European Society for Human Reproduction and Embryology (ESHRE) in Istanbul, was not big enough to tease out the differences between the two types, he added.

Exactly why different types of fat have different effects on fertility is currently unclear, although Dr Chavarro said they were “known to have different effects on biological processes which may influence the outcome of assisted reproduction”.

Richard Kennedy, general secretary of the International Federation of Fertility Societies (IFFS), commented: “We know that many lifestyle activities can make it harder to conceive.

“This work reinforces the need for a good lifestyle for those trying to have a baby; eat and drink in moderation, and don’t smoke.”

Seaweed may fight tooth decay

Microbes found on seaweed could provide an unexpected weapon in the fight against tooth decay, scientists have said.

They used an enzyme isolated from the marine bacterium Bacillus licheniformis which they were originally researching for cleaning ships’ hulls.

Instead, the Newcastle University team will tell the Society for Applied Microbiology Summer Conference that it could have a range of medical applications, including teeth cleaning.

While toothpastes are effective, there are still hard-to-reach areas between teeth where the bacteria in plaque can erode enamel, causing cavities.

Dr Nicholas Jakubovics of Newcastle University’s School of Dental Sciences believes better products offering more effective treatment can be made using the enzyme.

He said: “Plaque on your teeth is made up of bacteria which join together to colonise an area in a bid to push out any potential competitors.

“Traditional toothpastes work by scrubbing off the plaque containing the bacteria – but that’s not always effective – which is why people who religiously clean their teeth can still develop cavities.

Seaweed

Seaweed

“Work in a test tube has shown that this enzyme can cut through the plaque or layer of bacteria and we want to harness this power into a paste, mouthwash or denture cleaning solution.”

When threatened, bacteria shield themselves in a slimy protective barrier known as a biofilm.

It is made up of bacteria held together by a web of extracellular DNA which binds the bacteria to each other and to a solid surface – in this case in the plaque around the teeth and gums.


The biofilm protects the bacteria from attack by brushing, chemicals or even antibiotics.

But after studying Bacillus licheniformis, which is found on the surface of seaweed, Newcastle University scientists found that when the bacteria want to move on, they release an enzyme which breaks down the external DNA. That breaks up the biofilm and releases the bacteria from the web.

Professor Burgess, who led the research, said: “It’s an amazing phenomenon. The enzyme breaks up and removes the bacteria present in plaque and importantly, it can prevent the build up of plaque too.

“When I initially began researching how to break down these layers of bacteria, I was interested in how we could keep the hulls of ships clear but we soon realised that the mechanism we had discovered had much wider uses.

“If we can contain it within a toothpaste we would be creating a product which could prevent tooth decay.

“This is just one of the uses we are developing for the enzyme as it has huge potential such as in helping keep clean medical implants such as artificial hips and speech valves which also suffer from biofilm infection.”

The team will now look to collaborate with industry to carry out more tests and product development.