Comments on: Statins and prostate cancer http://lancastria.net/blog/statins-and-prostate-cancer.html Neuschwanstein, a castle that belongs in Blackburn Lancashire less the 4000 holes Fri, 18 May 2012 05:09:50 +0000 hourly 1 http://wordpress.org/?v=3.3.2 By: Neuschwanstein http://lancastria.net/blog/statins-and-prostate-cancer.html#comment-704 Neuschwanstein Mon, 20 Sep 2010 23:00:14 +0000 http://lancastria.net/blog/?p=3764#comment-704 A drug commonly prescribed for people with high cholesterol may also be effective in treating prostate cancer, according to new research by Dr. Xiao-Yan Wen at St. Michael's Hospital. Rosuvastatin -- a statin drug sold as Crestor -- suppressed the growth of transplanted human prostate cancer cells in mice. "Our data provided solid pre-clinical evidence and a strong rationale for clinical trials of statins in the treatment of prostate cancer," said Wen, whose research appears in the September issue of European Urology, the journal of the European Association of Urology. Prostate cancer is the most common cancer in Canadian men -- one in seven men will develop the disease during his lifetime and one in 27 will die from it. Despite improvements in treatments such as surgery, radiation and chemotherapy, many patients still progress to advanced stages. Recent clinical trials have shown encouraging results regarding the use of angiogenic inhibitors -- substances that prevent the growth of blood vessels that feed tumors. A drug commonly prescribed for people with high cholesterol may also be effective in treating prostate cancer, according to new research by Dr. Xiao-Yan Wen at St. Michael’s Hospital.

Rosuvastatin — a statin drug sold as Crestor — suppressed the growth of transplanted human prostate cancer cells in mice.

“Our data provided solid pre-clinical evidence and a strong rationale for clinical trials of statins in the treatment of prostate cancer,” said Wen, whose research appears in the September issue of European Urology, the journal of the European Association of Urology.

Prostate cancer is the most common cancer in Canadian men — one in seven men will develop the disease during his lifetime and one in 27 will die from it. Despite improvements in treatments such as surgery, radiation and chemotherapy, many patients still progress to advanced stages.

Recent clinical trials have shown encouraging results regarding the use of angiogenic inhibitors — substances that prevent the growth of blood vessels that feed tumors.

]]> By: Neuschwanstein http://lancastria.net/blog/statins-and-prostate-cancer.html#comment-686 Neuschwanstein Mon, 20 Sep 2010 19:41:36 +0000 http://lancastria.net/blog/?p=3764#comment-686 Scientists from an Israeli institute are developing a novel breath test that can detect early signs of breast, lung, bowel and prostate cancer. The team believes that further work could lead to a cheap, portable "electronic nose" that can help doctors diagnose disease early. "This study shows that an 'electronic nose' can distinguish between healthy and malignant breath, and can also differentiate between the breath of patients with different cancer types," express.co.uk quoted Professor Abraham Kuten, one of the researchers at the Technion - Israel Institute of Technology in Haifa, as saying. "If we can confirm these initial results in large-scale studies, this new technology could become a simple tool for early diagnosis of cancer along with imaging. It could also be an easy way to assess and monitor the effectiveness of cancer treatment and detect relapses earlier," Kuten added. During the study, scientists carried out tests on 177 volunteers including healthy participants and patients with different cancers aged between 20 and 75. The research saw people breathe into a mouthpiece to have a sample collected. "Pulses" of breath were then passed over sensors that can detect minute amounts of chemicals before computers analysed the data. The study appears in the British Journal of Cancer. Scientists from an Israeli institute are developing a novel breath test that can detect early signs of breast, lung, bowel and prostate cancer.

The team believes that further work could lead to a cheap, portable “electronic nose” that can help doctors diagnose disease early.

“This study shows that an ‘electronic nose’ can distinguish between healthy and malignant breath, and can also differentiate between the breath of patients with different cancer types,” express.co.uk quoted Professor Abraham Kuten, one of the researchers at the Technion – Israel Institute of Technology in Haifa, as saying.

“If we can confirm these initial results in large-scale studies, this new technology could become a simple tool for early diagnosis of cancer along with imaging. It could also be an easy way to assess and monitor the effectiveness of cancer treatment and detect relapses earlier,” Kuten added.

During the study, scientists carried out tests on 177 volunteers including healthy participants and patients with different cancers aged between 20 and 75.

The research saw people breathe into a mouthpiece to have a sample collected. “Pulses” of breath were then passed over sensors that can detect minute amounts of chemicals before computers analysed the data.

The study appears in the British Journal of Cancer.

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