Tag Archives: anthocyanins

Berry wine and type 2 diabetes

A drink made from berry wine could help diabetics cope with their condition, say researchers.

People with type 2 diabetes struggle to control their blood sugar levels as their bodies do not produce enough insulin.

As a result they must be careful how many carbohydrate-rich foods they eat as the body turns them into glucose, making blood sugar levels rise.

Now a study from the University of Illinois, has found that compounds found in both blueberry and blackberry wines inhibit two enzymes that are involved in the body’s absorption of carbohydrates.

The team said lab tests revealed a blueberry-blackberry blend of wine inhibited the carb-degrading enzymes, known as alpha-amylase and alpha-glucosidase, almost as much as an anti-diabetes drug.

They now hope to create a non-alcoholic fermented fruit drink that keeps blood sugar levels low but also contains anti-inflammatory compounds found in the original wine.

In a second study, graduate Michelle Johnson measured the antioxidant, polyphenol, and anthocyanin levels in blueberry and blackberry wines. Her proposed blend contains an abundance of these bioactive compounds, which add to its healthful properties.

Berries

Berries

The researchers are particularly interested in the ability of anthocyanins to reduce inflammation, which contributes to the development of many chronic illnesses, including cancer, metabolic disease, and cardiovascular disease.

To that end, they are experimenting with the berries’ effects on inflammatory cells, and they have found that anthocyanins reduce markers associated with the inflammatory response.

‘Preliminary studies have indicated that anthocyanins may have a positive effect on cognition and overall brain health while protecting against some of the effects of aging, such as Alzheimer’s disease and memory loss. These berries have some very intriguing components,’ said Professor Elvira de Mejia.


She added that the bioactive ingredients could also be added to any prepared beverage to give it colour, flavor, and nutritional punch, making them useful to the food industry.

Diabetes occurs when the body is no longer able to control the level of sugar in the blood.

Type 1 diabetes is when the body produces no insulin, and affects one in 10 with the condition. It usually develops before a person turns 40. Patients have to take insulin injections for life to manage the condition.

Type 2 diabetes affects nine out of 10 people with the condition. It occurs when the body does not produce enough insulin to function properly, or the body’s cells do not react to insulin. This is known as resistance. It usually affects those aged over 40 and is related to lifestyle factors such as obesity and heavy drinking.

It can be treated with lifestyle changes such as a healthy diet and regular exercise, however sometimes medication is needed as well. It is also progressive so can get worse over time.

Left untreated, it can cause a host of health problems including heart disease, stroke, nerve damage and blindness.

Peaches fight obesity

Peaches and plums have bioactive compounds that can fight off obesity-related diabetes and cardiovascular diseases, says a new study.

The study showed that the compounds in such fruits could be a weapon against “metabolic syndrome”, in which obesity and inflammation lead to serious health issues, according to Luis Cisneros-Zevallos, Texas AgriLife Research food scientist.

“In recent years, obesity has become a major concern in society due to the health problems associated to it,” said Cisneros-Zevallos, also associate professor at Texas A and M University.

“In the US, statistics show that around 30 percent of the population is overweight or obese, and these cases are increasing every year in alarming numbers,” added Cisneros-Zevallos, according to a Texas statement.

While he acknowledged that lifestyle, genetic predisposition and diet play a major role in one’s tendency toward obesity, “the major concern about obesity is the associated disease known as metabolic syndrome.”

Peaches

Peaches

“Our studies have shown that stone fruits – peaches, plums and nectarines – have bioactive compounds that can potentially fight the syndrome,” Cisneros-Zevallos said.

“Our work indicates that phenolic compounds present in these fruits have anti-obesity, anti-inflammatory and anti-diabetic properties in different cell lines and may also reduce the oxidation of bad cholesterol LDL which is associated to cardiovascular disease.”


What is unique to these fruits, he said, is that their mixture of the bioactive compounds work simultaneously within the different components of the disease.

“Our work shows that the four major phenolic groups – anthocyanins, clorogenic acids, quercetin derivatives and catechins – work on different cells – fat cells, macrophages and vascular endothelial cells,” he explained. “They modulate different expressions of genes and proteins depending on the type of compound.”

“However, at the same time, all of them are working simultaneously in different fronts against the components of the disease, including obesity, inflammation, diabetes and cardiovascular disease,” he explained.