Tag Archives: blood lipid levels

Dark chocolate and cardiovascular health

Consuming dark chocolate in moderate quantities may reduce the risk of cardiovascular disease, a new study has revealed.

Chocolate is a great source of myriad substances that scientists think might impart important health benefits. For instance, it contains compounds called “flavanols” that appear to play a variety of bodily roles including those related to their potent antioxidant and anti-inflammatory actions.

Many large-scale human studies have documented a statistical correlation between flavanol intake and risk for cardiovascular disease.

And animal studies suggest that this relationship may be due to the physiologic effects that flavanols have on chronic inflammation, blood vessel health, and circulating lipid levels.

However, few controlled human intervention studies have been conducted to test the direct effect of chocolate consumption on these variables.

To help fill this knowledge gap, researchers at San Diego State University tested their hypothesis that chocolate, in particular dark chocolate which contains higher levels of flavanols than milk chocolate, may protect against the risk of cardiovascular disease by lowering blood pressure, blood flow, and improving blood lipid levels.

Chocolate

Chocolate

In this prospective, controlled human intervention study, 31 fortunate subjects were assigned randomly to consume either a daily serving (50 grams) of either regular dark chocolate (70 percent cocoa), dark chocolate (70 percent cocoa) that had been overheated or “bloomed,” or white chocolate (0 percent cocoa).

The subjects were asked to consume the chocolate for 15 days. Blood pressure, forearm skin blood flow, circulating lipid profiles, and blood glucose levels were recorded at the beginning and end of the study.


When compared to participants assigned to the white chocolate group, those consuming either form of dark chocolate had lower blood glucose and low-density lipoprotein cholesterol (LDL, the “bad” form) levels coupled with higher high-density lipoprotein cholesterol (HDL, the “good” form).

The researchers concluded that dark chocolate may reduce the risk of cardiovascular disease by improving glucose levels and lipid profiles.

However, they cautioned that—although habitual dark chocolate consumption may benefit one’s health by reducing the risk of cardiovascular disease—it must be eaten in moderation because it can easily increase daily amounts of saturated fat and calories.

“We had great compliance with our study subjects because everybody wanted to eat chocolate. We actually had to tell them not to eat more than 50 grams a day,” the authors commented.

The group reports that it is planning follow-up studies involving more subjects and a longer duration of chocolate consumption.

Cholesterol levels and depression in the elderly

Most people know that high cholesterol levels place them at increased risk for heart disease and stroke. Prior research has shown that particular types of strokes contribute to one’s risk for depression, and that abnormal blood lipid levels can increase the risk of depression in the elderly.

However, new findings by French researchers, published in Biological Psychiatry, suggest the link between increased cholesterol and depression may be complicated. They evaluated a large population of elderly men and women (aged 65 and over) over a seven year follow-up period, assessing them for symptoms of depression and measuring their lipid levels.

Cholestero

Cholestero

They found that, in women, depression was associated with low levels of the “good” form of cholesterol, high density lipoprotein (HDL). This disturbance in their cholesterol levels put them at higher risk for vascular disease, including stroke, by increasing their risk for developing lesions in their blood vessels called atherosclerotic plaques.


In contrast, the men who were at greater risk of depression had low levels of the “bad” form of cholesterol, low density lipoprotein (LDL). This was especially true for those men with a genetic vulnerability to depression related to a serotonin transporter gene.

This finding in men raises important considerations. Although this pattern of low LDL levels seemingly protects them from developing cardiovascular diseases or strokes, this study suggests that it increases their mental health risk at the same time.