Tag Archives: Environment

Pesticides linked to childhood cancers

Pesticides and other poisonous chemicals used in growing fruit and veg could be putting young children at risk of developing cancer in later life, say scientists.

Pre-school children are in particular danger of exposure to the dangerous compounds, a U.S. study found.

Research leader Professor Irva Hertz-Picciotto, of California University in Davis, said: ‘Contaminants get into our food in a variety of ways. They can be chemicals that have nothing to do with the food or byproducts from processing. We wanted to understand the dietary pathway pesticides, metals and other toxins take to get into the body.’

A study of 364 children – 207 of whom were under-five – found safety consumption benchmarks were exceeded for arsenic, dieldrin, DDE and dioxins.

In addition more than 95 per cent of pre-school children exceeded non-cancer risk levels for acrylamide – a cooking byproduct often found in processed foods like potato and tortilla chips. Non-cancer effects include the death of cells.

Pesticide exposure was particularly high in tomatoes, peaches, apples, peppers, grapes, lettuce, broccoli, strawberries, spinach, dairy, pears, green beans and celery.

Study leader Dr Rainbow Vogt said: ‘We focused on children because early exposure can have long-term effects on disease outcomes.

‘Currently the US Environmental Protection Agency only measures risk based on exposures of individual contaminants.

‘We wanted to understand the cumulative risk from dietary contaminants. The results of this study demonstrate a need to prevent exposure to multiple toxins in young children to lower their cancer risk.’

Some pesticides can be removed from fruit and vegetables through washing and light scrubbing.

The researchers used data from the 2007 Study of Use of Products and Exposure-Related Behaviour (SUPERB) which surveyed households in California with children between two and five to determine how their diets, and other factors, contribute to toxic exposure.

Specifically SUPERB homed in on 44 foods known to have high concentrations of toxic compounds.

Intensive farming

Intensive farming

This included the metals arsenic, lead and mercury, pesticides chlorpyrifos, permethrin and endosulfan, persistent organic pollutants dioxin, DDT, dieldrin and chlordane and the food processing byproduct acrylamide.

Toxin levels in specific foods were determined through the Total Diet Study in the US that determines levels of various contaminants and nutrients in foods and other databases.

Prof Hertz-Picciotto said: ‘We need to be especially careful about children because they tend to be more vulnerable to many of these chemicals and their effects on the developing brain.’


The study published in Environmental Health outlines strategies to lower family exposure. For example, organic produce has lower pesticide levels.
In addition, toxin types vary in different foods. Certain pesticides may be found in lettuce and broccoli, while others affect peaches and apples.

Prof Hertz-Picciotto said: ‘Varying our diet and our children’s diet could help reduce exposure.

‘Because different foods are treated differently at the source, dietary variation can help protect us from accumulating too much of any one toxin.’

Study co-author Prof Deborah Bennett said: ‘Acrilomides come from chips and other processed grains.

‘Even if we set aside the potential toxins in these foods, we probably shouldn’t be eating large amounts of them anyway.

‘However, we should be eating fruits, vegetables and fish, which are generally healthy foods. We just need to be more careful in how we approach them.’

Eleanor Barrie, Cancer Research UK’s science information manager, said: ‘This study is small and was conducted in California so it doesn’t tell us anything about levels of particular chemicals found in foods in the UK.

‘It’s really important to remember that the levels of pesticides found in fruit and vegetables are usually very low, and there is no evidence that eating these small amounts of pesticides increases the risk of cancer.

‘In fact, eating lots of fruit and vegetables actually reduces the risk of some types of cancer, so it’s a good idea to get your five-a-day.’

Heart repairs

The secret to “mending broken hearts” has been discovered by scientists examining ways of repairing damaged tissue after heart attacks.

Injecting proteins similar to insulin directly into the heart can cause damaged cells to repair themselves and begin regenerating again, researchers said.

Tests on pigs showed that the dormant cells could begin regrowth following a “regenerative medicine” treatment using certain growth factors – naturally occurring proteins which cells use to communicate with their environment.

Experts from Liverpool John Moores University (LJMU) said the four-year study presented a “significantly different” therapy to those currently being developed by scientists.

The findings, produced with teams from Italy and Spain, could lead to simple and affordable treatments for heart attacks, they said.

Dr Bernardo Nadal-Ginard, Director of LJMU Stem Cell & Regenerative Biology Unit, said approaches currently being pursued in clinical trials were “time consuming” and “expensive”.

Heart disease

Heart disease

He said: “It is unlikely that they will have a major impact on the treatment of life-threatening diseases affecting millions of people, such as heart disease and failure.

“In contrast, this new approach by LJMU could ultimately lead to a clinical myocardial regenerative therapy which is effective, simple, affordable, readily and widely available and easy to apply and compatible with the current clinical standard of cardiac care.”

Dr Nadal-Ginard said the research shows that injecting growth factors IGF-1 and HGF caused significant “anatomical, histological and physiological” regeneration of damaged hearts and “sets the path” for testing clinical trials.


Another member of the LJMU BioStem research team, Dr Georgina May Ellison, said funding had been secured for clinical tests of the new method to begin at the Vall d’Hebron University Hospital in Barcelona.

She said: “We have obtained very encouraging evidence from this the preclinical data.

“If we can get funding we would want to run clinical tests the UK. We are in talks with funding bodies and the Liverpool Heart and Chest Hospital to do those clinical tests there.”

“I think it holds-out the highest promise that we have on cellular therapy that is out there at the moment.”