Tag Archives: heart problems

Energy drinks linked to hypertension

Energy drinks may cause high blood pressure and potentially lethal heart problems, new research has found.

Doctors are warning people with high blood pressure to ‘use caution and judgment’ before downing the drinks, after finding they may increase blood pressure and disturb the heart’s natural rhythm.

American researchers analysed data from seven previously published studies to determine how consuming energy drinks might impact heart health.

The pooled studies included healthy patients, aged 18 to 45.

In the first part of the pooled analysis, the researchers examined the QT interval – a segment of the heart’s rhythm – of 93 people who had just consumed one to three cans of energy drinks.

They found that the QT interval was 10 milliseconds longer for those who had consumed the energy drinks.

The QT interval describes a segment of the heart’s rhythm on an electrocardiogram; when prolonged, it can cause serious irregular heartbeats or sudden cardiac death.

Lead author Doctor Sachin Shah, assistant professor at University of the Pacific in the United States, said: ‘Doctors are generally concerned if patients experience an additional 30 milliseconds in their QT interval from baseline.

‘QT prolongation is associated with life-threatening arrhythmias. The finding that energy drinks could prolong the QT, in light of the reports of sudden cardiac death, warrants further investigation.’

Energy drinks

Energy drinks

The researchers also found that the systolic blood pressure, the top number in a blood pressure reading, increased an average of 3.5 points in a pool of 132 participants.


Dr Shah added: ‘The correlation between energy drinks and increased systolic blood pressure is convincing and concerning, and more studies are needed to assess the impact on the heart rhythm.

‘Patients with high blood pressures or long QT syndrome should use caution and judgment before consuming an energy drink.

‘Since energy drinks also contain caffeine, people who do not normally drink much caffeine might have an exaggerated increase in blood pressure.

‘People with health concerns or those who are older might have more heart-related side effects from energy drinks.’

The findings were presented at the American Heart Association’s Epidemiology and Prevention conference.

New tuberculosis drug

Johnson ‘N’ Johnson has won approval from The Food and Drug Administration for a tuberculosis drug that is the first new medicine to fight the deadly infection in more than four decades.

According to ABC News, the agency approved the company’s pill, Sirturo, for use with older drugs to fight a hard-to-treat strain of tuberculosis that has not responded to other medications.

But the agency cautioned that the drug carries risks of potentially deadly heart problems and should be prescribed carefully by doctors, the report added.

Roughly one-third of the world’s population is estimated to be infected with the bacteria causing tuberculosis. The disease is rare in the U.S., but kills about 1.4 million people a year worldwide. About 60 percent of all cases are concentrated in China, India, Russia and Eastern Europe.

Sirturo, known chemically as bedaquiline, is the first medicine specifically designed for treating multidrug-resistant tuberculosis. That’s a form of the disease that cannot be treated with at least two of the four primary antibiotics used for tuberculosis.

The standard drugs used to fight the disease were developed in the 1950s and 1960s.

Tuberculosis

Tuberculosis

Since the antibiotics used to treat tuberculosis have been around for at least 40 years, the bacterium has become more and more resistant to what we have, said Chrispin Kambili, global medical affairs leader for Johnson ‘N’ Johnson Janssen division.

The drug carries a boxed warning indicating that it can interfere with the heart’s electrical activity, potentially leading to fatal heart rhythms.


Sirturo can provide much-needed treatment for patients who don’t have other therapeutic options available, said Edward Cox, director of the FDA’s antibacterial drugs office.

However, he noted that because the drug also carries some significant risks, doctors should make sure they use it appropriately and only in patients who don’t have other treatment options.

The FDA said it approved the drug based on two mid-stage studies enrolling 440 patients taking Sirturo. Both studies were designed to measure how long it takes patients to be free of tuberculosis.

Results from the first trial showed most patients taking Sirturo plus older drugs were cured after 83 days, compared with 125 days for those taking a placebo plus older drugs. The second study showed most Sirturo patients were cured after 57 days.