Tag Archives: osteocalcin

Mediterranean diet protects bones from osteoporosis

Following a Mediterranean diet rich in virgin olive oil may protect bones and keep them strong.

There was a time when olive oil was something you only really encountered while on holiday abroad, now it’s everywhere – drizzled on salads, asparagus or peppers, mopped up with crusty bread or mixed into pestos. And a good thing too, because even as it seems as though all the benefits of the oil must already have been found, new research reveals that it supports your bones too.

Researchers from the Hospital Dr Josep Trueta in Spain looked at data from a group of 127 randomly selected men aged between 55 and 80 to assess the effect of the Mediterranean diet on a specific serum – osteocalcin – that has a protective effect on bones.

Mediterranean diet

Mediterranean diet

As the incidence of osteoporosis is lower in areas where people eat a Mediterranean-based diet, the researchers theorised that the diet might be linked to this difference. And it seems they could be right. The study participants were put into different groups, each with its own special diet – Mediterranean diet with mixed nuts, the same diet but with virgin olive oil and a low-fat diet.


After two years, the study participants who had had virgin olive oil along with the Mediterranean diet showed improved osteocalcin levels. They also showed other signs of improvements in bone strength, measured using other bone formation markers. Furthermore, serum calcium decreased significantly in the other two groups indicating that olive oil, when combined with the Mediterranean diet, seems to have the greatest effect.

Mediterranean diet protects your bones

Swapping to a Mediterranean diet rich in olive oil could help protect your bones in later life, claim researchers.

Just two years of eating like the Spanish and Italians who use olive oil rather than less healthy fats may preserve or even build bone in older people, says a new study.

The Mediterranean diet is regarded as the classic eating habits of populations from countries in southern Europe, even though fewer inhabitants follow it today.

It has been thought to improve heart health and stave off cancer because it is high in fruit, vegetables, fish, nuts, whole grains and ‘healthy’ fats such as those in olive oil, while low in red meat and dairy products.

But a new study shows further benefits to bones as people eating more olive oil had higher levels of the hormone osteocalcin in their blood – a marker linked to better bone strength.

Previous studies have shown that Mediterranean countries have lower rates of osteoporosis compared with northern European nations, which could be due to different dietary factors.

Osteoporosis is often termed the ‘silent disease’ as there are no symptoms prior to a fracture. However, once a person has broken a bone, their risk of breaking another bone – a fragility fracture – increases dramatically.

Around 300,000 fragility fractures occur every year in the UK, and hip fractures lead to 1150 deaths every month.

In the study, 127 people aged 55 to 80 regarded as high risk heart patients took part in the Prevencion con Dieta Mediterranea (PREDIMED) study.

Mediterranean diet

Mediterranean diet

They had type 2 diabetes, high blood pressure or other cardiovascular risk factors, says a report in the Journal of Clinical Endocrinology and Metabolism.

They were randomly assigned to three different diets: Mediterranean diet with mixed nuts, Mediterranean diet with at least 50ml of virgin olive oil a day, and a low-fat diet.

People on the olive oil diet were told to use it for cooking and dressing salads, eat more fruit and vegetables, eat less red meat, avoid butter, cream, fast food, cakes, and, if they were alcohol drinkers, to consume moderate amounts of red wine.

The results after two years showed those on the Mediterranean diet with olive oil had a significant increase in concentrations of osteocalcin and other bone formation markers, and no other diet had the same effect.

Dr Jose Manuel Fernandez-Real, of Hospital Dr Josep Trueta in Girona, Spain, said the consumption of olive oil has been already been linked to prevention of osteoporosis in experimental research, but the new study looked at direct effects in people.


He said ‘This is the first randomised study which demonstrates that olive oil preserves bone, at least as inferred by circulating bone markers, in humans.

‘It’s important to note that circulating osteocalcin was associated with preserved insulin secretion in subjects taking olive oil.

‘Osteocalcin has also been described to increase insulin secretion in experimental models.’

Olive oil contains omega-6 fats, a form of ‘healthy’ polyunsaturates which blocks the body’s response to inflammation in chronic conditions such as heart disease and arthritis.

It also reduces blood pressure and improves the ratio of good to bad blood fats.

Dieticians say the Mediterranean diet also appears to improve vascular function, the flexibility of cells lining the walls of blood vessels, particularly in the heart and circulatory system.

The diet is known to fight inflammation and repair oxygen-related cell damage.

Previous research has found strict adherence to a Mediterranean diet could help stave off memory loss and Alzheimer’s.