Tag Archives: psychotropic drugs

Prozac dangers

Taking happy pills before driving makes you more prone to accidents, researchers claim.

They have found that taking common antidepressants such as Prozac and Seroxat heightens the risk by 70 per cent.

Even patients who have only been on the pills for a few hours are far more likely to have a crash if they get behind the wheel.

Although some manufacturers put warning notices on boxes telling patients their judgment may be impaired, they don’t specifically tell them not to drive.

But it is now thought that the same chemical changes that improve mood among those who take the pills also slows down reaction times.

Researchers say the study shows that doctors should be banning patients from getting behind the wheel as soon as they put them on a course of drugs.

Recently the number prescriptions for antidepressants have soared and last year nearly 50 million were handed out, a rise of a quarter in four years.

Campaigners have blamed the economic woes but also say GPs have become better at diagnosing the illness so are more likely to hand out the pills.

Prozac

Prozac

Researchers from the University of Taiwan looked at data on 36,000 and compared the likelihood of them having an accident to whether they were on antidepressants.

They also looked at other drugs including sleeping pills and antipsychotics which are taken for mental illnesses as well as dementia.

Collectively all of these drugs are known as psychotropic medication which means they affect mental activity or behaviour.


Those taking a common group of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) which include Prozac and Seroxat were 72 per cent more at risk.

Even patients who had only started the course of drugs that day were 74 per cent more likely to have an accident within 24 hours than those not on medication.

Those on a type of sleeping pills called benzodiazepines were 56 per cent more at risk of accidents while antipsychotics increased the likelihood by just 9 per cent.

Lead researcher Hui-Ju Tsai, who is based at the National Health Research Institutes in Zhunan, Taiwan, said: ‘ Our findings underscore that people taking these psychotropic drugs should pay increased attention to their driving performance in order to prevent motor vehicle accidents.

‘Doctors and pharmacists should choose safer treatments, provide their patients with accurate information and consider advising them not to drive while taking certain psychotropic medications.’

Designer drug may treat blood cancers

THE designer drug Ecstasy has been developed into a potent medical treatment that could be the key to tackling blood cancers. It may help save thousands of lives each year.

Scientists at the University of Birmingham have discovered that a reworked form of the drug MDMA – commonly known as Ecstasy – has potential as a cancer-killing agent for treating leukaemia, lymphoma and myeloma.

Research published online in the journal Investigational New Drugs reveals significant success in “redesigning the designer drug” which they now hope can be produced in a safe form to treat patients.

Six years ago scientists at the university found that half of the cancers affecting white blood cells responded in the test tube to the growth-suppressing properties of “psychotropic” drugs.

Cancer cells

Cancer cells

These included weight loss pills, Prozac-type anti-depressants, and amphetamine derivatives such as MDMA.

Professor John Gordon, of the university’s School of Immunology and Infection, said: “This is an exciting next step towards using a modified form of MDMA to help people suffering from blood cancer. While we would not wish to give people false hope, the results of this research hold the potential for improvements in treatments in years to come.”

Dr David Grant, scientific director of the charity Leukaemia & Lymphoma Research, which part-funded the study, said: “The prospect of being able to target blood cancer with a drug derived from Ecstasy is a genuinely exciting proposition.

“Many types of lymphoma remain hard to treat and non-toxic drugs which are both effective and have few side-effects are desperately needed.


“Further work is required but this research is a significant step forward in developing a potential new cancer drug.”

According to the latest statistics almost 12,000 people are diagnosed with blood cancers. They kill nearly 26,000 each year.

Chemotherapy is currently the main course of treatment for blood cancers. But in many cases it will fail because the cancer cells have developed defences against the drugs.

One of the major problems in creating new treatments for blood cancers is that high levels of a key protein called BCL2 protect the cancer cells from being killed.

The new Ecstasy-based treatment can bypass this defence mechanism.