Tag Archives: spice

Curry ingredient may fight bowel cancer

A chemical found in curry is to be tested for its ability to kill bowel cancer tumours in patients.

Curcumin, which is found in the spice turmeric, has been linked to a range of health benefits.

Studies have already shown that it can beat cancer cells grown in a laboratory and benefits have been suggested in stroke and dementia patients as well.

Now a trial at hospitals in Leicester will investigating giving curcumin alongside chemotherapy drugs.

About 40,000 people are diagnosed with bowel cancer in the UK each year.

If the disease spreads around the body, patients are normally given a combination of three chemotherapy drugs, but about half will not respond.

Forty patients at Leicester Royal Infirmary and Leicester General Hospital will take part in the trial, which will compare the effects of giving curcumin pills seven days before starting standard chemotherapy treatment.

Curry

Curry

Prof William Steward, who is leading the study, said animal tests combining the two were “100 times better” than either on their own and that had been the “major justification for cracking on” with the trial.


He said: “Once bowel cancer has spread it is very difficult to treat, partly because the side effects of chemotherapy can limit how long patients can have treatment.

“The prospect that curcumin might increase the sensitivity of cancer cells to chemotherapy is exciting because it could mean giving lower doses, so patients have fewer side effects and can keep having treatment for longer.

“This research is at a very early stage, but investigating the potential of plant chemicals to treat cancer is an intriguing area that we hope could provide clues to developing new drugs in the future.”

Joanna Reynolds, from Cancer Research UK, said: “By doing a clinical trial like this, we will find out more about the potential benefits of taking large amounts of curcumin, as well as any possible side effects this could have for cancer patients.”

Spice up your broccoli

Spicing up broccoli with horseradish or wasabi can enhance the vegetable’s cancer-fighting properties, according to the latest research.

Overcooking the vegetable instead of lightly steaming it for two to four minutes doesn’t necessarily ruin destroy broccoli’s cancer-fighting properties.

Instead these can be revived by adding traditional horseradish or the spicy Japanese variety which contain the enzyme myrosinase.

Professor Elizabeth Jeffery, a nutritionist at the Illinois University, spicing up the veg increases absorption in the upper part of the digestion system boosting its impact.

She said: ‘To get this effect, spice up your broccoli with broccoli sprouts, mustard, horseradish, or wasabi. The spicier, the better; that means it’s being effective.’

In the study, when fresh broccoli sprouts were eaten with broccoli powder, the scientists were able to measure bioactive compounds in the blood 30 minutes later.

Broccoli

Broccoli

When these peaked at three hours, they were much higher when the foods were eaten together than when either was eaten alone. Urine samples corroborated the blood results, according to Jenna Cramer, lead author of the study published in the British Journal of Nutrition .

‘However, this study shows that even if broccoli is overcooked, you can still boost its benefits by pairing it with another food that contains myrosinase,’ she said.

Broccoli powder doesn’t contain myrosinase, but it does contain the precursor to the anti-cancer agent sulforaphane.

But when eaten together, the sprouts were able to lend their myrosinase to the powder.

As predicted, both foods produced sulforaphane and provided greater anti-cancer benefit, Jeffery said.


Other foods that will boost broccoli’s benefits if they are paired together include radishes, cabbage, arugula, watercress, and Brussels sprouts.

‘Here’s another benefit of protecting and enhancing the myrosinase in your foods,’ Jeffery said. ‘If myrosinase is present, sulforaphane is released in the ilium, the first part of your digestive system. Absorption happens well and quickly there, which is why we saw bioactivity in 30 minutes.’

Scientists say that as little as three to five servings of broccoli a week provide a cancer-protective benefit.

‘But it pays to spice it up for added benefits and find ways to make it appealing so you don’t mind eating it if you’re not a broccoli fan. I add fresh broccoli sprouts to sandwiches and add them as one of my pizza toppings after the pie is out of the oven,’ Cramer said.