Tag Archives: statin

Statins may reduce risk of prostate cancer

Taking statins to cut cholesterol can help to reduce the risk of developing prostate cancer, says researchers.

The findings back up previous studies suggesting that controlling cholesterol, a ‘key nutrient’ for cancer cells, can have multiple benefits.

Study author Stephen Marcella said: ‘People may be on these medications for their heart but it may be doing them some good for their prostate.’

With colleagues in New Jersey, U.S., he examined the records of 380 men who had died of prostate cancer and another 380 of similar ages.

Dr Marcella and his colleagues collected the medical records of 380 men who had died of prostate cancer and another 380 of the same age and race without prostate cancer or with non-lethal cancer.

Most of the men were white and in their mid- to late-60s, on average and close to one in four of the men in both groups combined had ever taken a statin.

The researchers found that men who died of prostate cancer were half as likely to have taken a statin at any time, and for any duration, than men in the ‘control’ group.

Statins

Statins

When they accounted for whether or not men were overweight and their other health problems and medications, it turned out that those with fatal cancers were 63 per cent less likely to have ever taken a statin, according to findings published in the journal Cancer.

‘If a person’s on the fence about taking a statin medication for their heart, this is another potential benefit they may have by taking one of these,’ he said.

But, Dr Marcella added, ‘I would not tell a person if they don’t have a risk of heart disease… to take a statin just to prevent lethal prostate cancer.’

Around seven million Britons currently take statins.


Meanwhile some 34,593 men were diagnosed with prostate cancer last year – a ten per cent annual rise.

The illness is by far the most common form of cancer in men and one in nine will develop it at some point during their lives.

The researchers also found that while high-potency, newer statins were linked to a decreased risk of fatal prostate cancer, the same was not so true of lower-potency drugs.

This suggests that it is something about the drugs themselves that lower men’s chances of dying from prostate cancer, Dr Marcella said.

The researchers added that cholesterol is a ‘key nutrient’ for cancer cells, so lower cholesterol levels in the body could prevent more aggressive forms of cancer from developing.

But they said that to prove that statins protect against aggressive cancer would require a much larger study in which cancer-free men, or those with early-stage disease, are randomly assigned to take statins or not and then tracked for years to see how many of them die from the disease.

Statins may treat Influenza

Statins, traditionally known as cholesterol-lowering drugs, may reduce mortality among patients hospitalized with influenza, according to a new study released online by The Journal of Infectious Diseases.

It is the first published observational study to evaluate the relationship between statin use and mortality in hospitalized patients with laboratory-confirmed influenza virus infection, according to Vanderbilt’s William Schaffner, M.D., professor and chair of Preventive Medicine.

“We may be able to combine statins with antiviral drugs to provide better treatment for patients seriously ill with influenza,” said Schaffner, who co-authored the study led by Meredith Vandermeer, MPH, of the Oregon Public Health Division.

Researchers studied adults who were hospitalized with laboratory-confirmed influenza from 2007-2008 to evaluate the association between patients who were prescribed statins and influenza-related deaths.

Statins

Statins

Among 3,043 hospitalized patients with laboratory-confirmed influenza, 33 percent were given statin medications prior to or during hospitalization. After adjusting for various factors, researchers found that patients not receiving statins were almost twice as likely to die from influenza as those who received the medication.


Schaffner stressed that receiving the influenza vaccine each year is still the best defense against influenza. The Centers for Disease Control and Prevention (CDC) estimates that between 5 percent and 20 percent of U.S. residents get the flu each year, and more than 20,000 persons are hospitalized for flu-related complications.