Mediterranean diet is better than statins

A Mediterranean diet is better than statins at slashing the risk of an early death for millions of Brits.

A landmark seven-year study found the healthy eating regime is twice as effective as the drugs alone at boosting the lifespan of heart patients.

Seven million Brits live with cardiovascular disease . The vast majority take statins every day, which can produce unwanted side effects.

The “extraordinary” findings were presented at the world’s biggest heart conference in Rome, Italy.

In the first ever study to look at the impact of a Med diet on heart patients, experts found a diet high in fruit , vegetables, fish, nuts and olive oil slashed the risk of an early death by 37%.

Previous research found just taking statins cuts mortality by 18%.

And leading experts said the discovery meant heart patients should be prescribed the Med diet before being given cholesterol-busting drugs.

Others hailed the breakthrough research as proof that the Med diet is “more powerful than any drug” and said it was “time for the NHS to embrace lifestyle medicine”.

Speaking at the annual congress of the European Society of Cardiology, Professor Giovanni de Gaetano, of the Neuromed Institute in Pozzilli, Italy, said: “We found that among those with a higher adherence to the Mediterranean diet, death from any cause was reduced by 37% in comparison to those who poorly adhered to this dietary regime.”

He added: “We know that taking drugs like statins for prevention can reduce mortality by around 20%.

“The message is that it is not only drugs that should be considered for secondary prevention, but also the Mediterranean diet.”

He also suggested that following the Med diet could reduce the need for drugs.

He added: “Adhering to the Mediterranean diet can reduce mortality for any cause to a large extent. It is a powerful means to reduce all causes of death.”

Speaking in Rome, he added: “The Mediterranean diet may be more effective than drugs .

“We are not saying exclude the use of drugs. We are saying that first of all doctors should consider diet before drugs.

“It could allow patients to get the benefits of statins but without the side effects.”

Lead author Dr Marialaura Bonaccio revealed: “The major contributors to mortality risk reduction were a higher consumption of vegetables, fish, fruits, nuts and monounsaturated fatty acids – that means olive oil.”

Researchers followed 1,200 Italians with heart disease over seven years.

Professor de Gaetano said: “The Mediterranean diet is widely recognised as one of the healthier nutrition habits in the world.

But so far research has focused on the general population, which is mainly composed of healthy people.

“What happens to people who have already suffered from cardiovascular disease? Is the Mediterranean diet optimal for them too?”

The study results, released for the first time this weekend, proved the answer is yes.

The 1,200 heart patients were among 25,000 participants enrolled into the MOLI-SANI project, a prospective epidemiological study that randomly recruited adults living in Molise, Italy.

Researchers recorded the food intake of the participants using the European Prospective Investigation into Cancer (EPIC) food frequency questionnaire.

Adherence to the Mediterranean diet was appraised with a 9-point Mediterranean diet score (MDS).




Over seven years, there were 208 deaths. After controlling for age, sex, education, exercise, smoking, blood pressure, cholesterol levels, diabetes and cancer, a 2-point increase in the Mediterranean diet score was linked with a 21% reduced risk of death.

When considered as a 3-level categorical variable, the top category – a score of 6 to 9 – of adherence to the Mediterranean diet was associated with a 37% lower risk of death compared to the bottom category (a score of 0-3).

A previous study of 92 trials involving 200,000 patients found that people with cardiovascular disease were 18% less likely to die early if they took statins.

Researchers said the next step would be to investigate why exactly the Mediterranean diet helps reduce the risk of dying early.

Mediterranean diet
Mediterranean diet

Professor de Gaetano concluded: “These results prompt us to investigate the mechanism(s) through which the Mediterranean diet may protect against death.

“This was an observational study so we cannot say that the effect is causal.

“We expect that dietary effects on mediators common to chronic diseases such as inflammation might result in the reduction of mortality from any cause but further research is needed.”

British experts said it was likely to be the “powerful anti-inflammatory effects” of the Mediterranean diet that slashes the risk of an early death.

Dr Aseem Malhotra, one of the world’s leading cardiologists, hailed the results as “extraordinary” and added that eating well is better than taking drugs for heart protection.

He said: “The results of this robust observational study are quite extraordinary and confirms previous randomised controlled trial data that the Mediterranean diet is more powerful than any drug at reducing death rates in patients with cardiovascular disease.




“It’s the powerful anti-inflammatory effects of foods such as olive oil, nuts, oily fish and vegetables where the benefits lie and unlike cholesterol-lowering statin drugs come without side effects.

He added: “It’s time for the NHS to embrace lifestyle medicine to rapidly save it from the collapse being predominantly driven by diet related disease.”

Professor Jeremy Pearson, Associate Medical Director of the British Heart Foundation, said: “It is good to know that even if you already have a history of cardiovascular disease, adhering to a Mediterranean diet reduces the risk of death.

“This study suggests that even if you are already receiving medical care, if you add a Mediterranean diet, it will have further benefit.

“Maintaining a healthy lifestyle, even if you have had a heart attack or stroke is really important and continues to benefit you.”

Leafy green veg may help fight glaucoma

Leafy greens like spinach, lettuce and kale could lower the risk of glaucoma by up to 30%, research has found.

A diet of nitrate-rich vegetables is good for blood circulation which means it could prevent primary open-angle glaucoma (POAG), one of four types of the condition, Harvard Medical School discovered.

Dr Jae Kang explained: “Higher dietary nitrate and green leafy vegetable intake was associated with a lower POAG risk.”

The study, published in the journal JAMA Ophthalmol, looked at more than 104,000 patients.

It found those who ate a nitrate-rich diet had lower levels of the rare condition, which involves chronic or acute sudden painful build-up of pressure in the eye.

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Increased pressure and a disruption in the flow of optic nerve blood flow have been implicated in POAG.

Previous studies suggested nitrate or nitrite, precursors for nitric oxide, is beneficial for blood circulation so scientists from Harvard Medical School looked at the link of diet and POAG.

Green vegetables
Green vegetables

Assistant Professor of Medicine Jae Kang said: “Evidence suggests that nitrate or nitrite is beneficial for blood circulation.

“Dietary nitrate is predominately derived from green leafy vegetables, which contribute approximately 80 per cent of nitrate intake.

“To our knowledge, dietary nitrate intake as a specific nutrient has not been evaluated – therefore, we evalated it in a longer-than-25-year prospective study of 63,893 women and 41,094 men.




“These findings could have important implications if the association of higher dietary nitrate and green leafy vegetable intake with a lower POAG risk is confirmed.”

The study followed participants in the two studies who were over 40, free of POAG, and had results of eye examinations.

Information on diet was updated with questionnaires.

During follow-up, 1,483 incident cases of POAG were identified.

They were divided into five groups dependent upon nitrate levels in their diet.

It was found greater intake of dietary nitrate and green leafy vegetables was associated with a 20 per cent to 30 per cent lower POAG risk.